900064-Rev4
  • See more completely.
  • See more deeply.
  • See more of the esophagus.
900064-Rev4

The NvisionVLE Imaging System, with Advanced OCT, uses an optical signal acquisition and processing method to create more complete cross-sectional images—letting you evaluate 100% of the tissue in a 6cm scan to better inform your evaluation. 3mm deep. 6cm long. At a resolution of 7 microns. In real time. So you can do more than just look. You can see.

The NvisionVLE Imaging System is indicated for use as an imaging tool in the evaluation of human tissue microstructure, including esophageal tissue microstructure, by providing two-dimensional, cross-sectional, real-time depth visualization. The safety and effectiveness of this device for diagnostic analysis (i.e. differentiating normal versus specific abnormalities) in any tissue microstructure or specific disease has not been evaluated.


900064-Rev4

A streamlined procedure

The NvisionVLE Imaging System allows clinicians to evaluate the esophageal tissue microstructure in a groundbreaking manner, during a standard endoscopy procedure. The system performs a cross sectional scan through a 6cm length, 3mm deep, enabling visualization of tissue layers including the squamous mucosa, submucosa, and muscularis propria, as well as identification of suspicious areas within the tissue. All so you can provide a more thorough evaluation—potentially leading to improved biopsy targeting for diagnosis by histopathology and more complete information to determine the best treatment for your patients.


900064-Rev4

An advanced system

NvisionVLE Imaging System Advantages:

  • Captures images up to 3mm beneath the mucosa at a 7 micron resolution in real time—unlike white light endoscopy, which can only image surface detail
  • Offers a full-field view (~10,000mm2), as opposed to a “point” image typically obtained with confocal microscopy (0.25mm2)
  • Advanced Optical Coherence Tomography (OCT) imaging delivers up to 25X higher resolution than endoscopic ultrasound
  • Provides a dramatic increase in imaging speed and improved image resolution, compared to first-generation OCT systems

3mm image depth

900064-Rev4

Image console & user interface

The NvisionVLE Imaging Console is designed with clinicians in mind:

  • User-friendly controls for physicians and support staff
  • Feature-rich user interface for intuitive navigation and high-resolution image management
  • Advanced OCT technology enables improved resolution and imaging speed
  • Rapid set-up and easy mobility

The NvisionVLE User Interface is designed for flexibility and functionality:

  • Visual options for better examination, including image magnification and inverse grayscale
  • Easy export of desired snapshots or videos from any portion of the imaging data
  • Straightforward correlation between the scanned image and anatomy to aid in targeting

900064-Rev4

A high-speed probe

The NvisionVLE Imaging System utilizes a single-use optical probe and lens system that rotates at high speed while retracting within the inner lumen.
Plus:

  • Balloon catheter facilitates optical probe positioning and centering
  • Available in 14mm, 17mm, and 20mm sizes to accommodate various anatomies
  • Atraumatic tip designed to gently flex when in contact with tissue
  • Compatible with endoscope channels 2.8mm or larger
  • Extremely low noise for polarization diverse balanced detection

Optical Probe Specs:

  • 7µm – High-resolution tissue imaging
  • >3mm – Near-infrared image depth
  • >6cm – Long-length image to capture area of interest
  • >10,000mm3 – Volumetric imaging in under 90 seconds
  • >105dB – Extremely high sensitivity; able to detect 1.0E-15 watts of light
  • >45dB – Wide dynamic range provides high contrast ratio
  • >500MBs – Real-time, high-speed data acquisition, reconstruction, and display

900064-Rev4

Reimbursement

The Current Procedural Terminology (CPT)* codes used for reimbursement of the VLE procedure are:

CPT 43206 Esophagoscopy, flexible, transoral; optical endomicroscopy
CPT 43252 Esophagogastroduodenoscopy, flexible, transoral; optical endomicroscopy
Both of these codes for upper GI procedures have been assigned to APC 419 for Hospital Outpatient Facility Reimbursement.

CPT 88375 Optical endomicroscopic image(s), interpretation and report, real-time or referred, each endoscopic session
This code, intended for the pathologist, has been assigned to APC 0342 for Hospital Outpatient Facility Reimbursement.

To receive the NvisionVLE™ Imaging System Reimbursement Guide, please complete this form or ask your local NinePoint Medical representative.

For more information about reimbursement, please contact us at reimbursement@ninepointmedical.com.

* CPT codes and descriptions only are copyright 2013 American Medical Association (AMA). All rights reserved. The AMA assumes no liability for data contained or not contained herein.

The coding, coverage, and payment information contained herein is gathered from various resources and is subject to change without notice. Nine Point Medical cannot guarantee success in obtaining third-party insurance payments. Third-party payment for medical products and services is affected by numerous factors. It is always the provider’s responsibility to determine and submit appropriate codes, charges, and modifiers for services that are rendered. Providers should contact their third-party payers for specific information on their coding, coverage, and payment policies.


900064-Rev4

A faster, better way of seeing

NinePoint’s NvisionVLE Imaging System is a groundbreaking convergence of superior optical imaging, innovative engineering techniques, and revolutionary information technology. At the heart of the system, Advanced Optical Coherence Tomography (OCT) technology provides physicians and pathologists with comprehensive, volumetric digital images of a patient’s esophagus. This next-generation technique enables much higher imaging speeds, combined with improved field-of-view and signal-to-noise ratio.

To download our complete bibliography on OCT technology click here.

To see the NvisionVLE instructions for use click here.

How Advanced OCT works

The (greatly simplified) fundamentals of Advanced OCT are shown in the above diagram. Similar to a traditional laser, the swept-source laser produces light of only one ‘color’ at any instant in time. However, unlike a traditional laser, the swept-source changes the color of its output light very rapidly in time.

The output light is split in two: one beam stays internal to the console, while the second is transmitted through the catheter and focused into the tissue. Some of the light is reflected back from physiological structures within the tissue, and this reflected light is collected by the catheter and returned to the console.

Inside the console, the reflected and internal beams are combined and interfere with each other. After some processing, the interference signal yields an axial line (‘A-line’) that records the intensity of reflections at each depth in the tissue. Combining many consecutive A-lines into an image provides a cross-sectional look at all the reflecting structures in the tissue.


900064-Rev4

A brief history of OCT

An OCT image is taken every second--over 40 million per year in opthalmology alone

The basic principles of Optical Coherence Tomography (OCT) were initially used within the fields of optical radar and optical telecommunications, among others. The technology expanded in the late 1980s when researchers began exploring applications for biological tissue imaging. Over the next decade, researchers around the world developed sub-categories of the technology, such as swept-source OCT, and began investigating ways to use OCT in different types of tissues and biomedical applications.

Today, commercial OCT systems are used regularly as an imaging standard in ophthalmology, cardiology, dermatology, and general research. NinePoint’s Advanced OCT technology, licensed from the Wellman Center for Photomedicine at Massachusetts General Hospital, initially focuses on esophageal and general imaging of tissue microstructure.

OCT timeline 1991-present

900064-Rev4

Filling an imaging gap

The ideal imaging system for esophageal surveillance would combine high-resolution scanning, depth, and volume to enable the identification and interrogation of both superficial and buried features.

SIZE OF BUBBLE DENOTES FIELD OF VIEW


900064-Rev4

Our vision

NinePoint Medical is positioned to improve patient care through the development of medical devices that enable high-resolution in-vivo imaging. Using advanced optical technologies, NinePoint Medical empowers treating physicians and pathologists to image cross-sectionally to visualize features at and below the mucosal surface, over very large areas. We deliver imaging information to support clinical decision-making relative to biopsy placement and treatment planning.


900064-Rev4

The NinePoints for Success

NinePoint Medical’s long-term vision for success is the convergence of Access, Diagnosis, and Treatment. A vision that leans on the ideals of the nine-point circle—a circle that passes through the nine significant points of any given triangle.
Here are our NinePoints for Success:

  1. Constantly create high-quality products that improve patient care
  2. Value high-quality innovation
  3. Be better than industry standard in the quality of our people and the efficiency of our operations
  4. Value relationships that build respect and foster teamwork
  5. Utilize good communication
  6. Create and maintain a positive work environment that is fun and rewarding to be a part of
  7. Cultivate individual responsibility and promote personal and professional growth
  8. Value diversity of people and opinion
  9. Make a difference

900064-Rev4

Management

NinePoint Medical brings together experts in medical device development,
imaging, optical technology, engineering, and medicine.



900064-Rev4

NinePoint Medical, Inc. is a privately-held medical device company located in Cambridge, MA. Our investment team includes:

thirdrockventures.com

Third Rock Ventures
www.thirdrockventures.com

prospectventures.com

Prospect Venture Partners
www.prospectventures.com

Contact: Judith Huber, Chief Financial Officer  JHuber@ninepointmedical.com


900064-Rev4

Press Releases

2014
2013
2012
2011
2010

900064-Rev4

Who you are. Who we hire.
How to apply.

You are an achiever. You want to make a difference. You recognize the breadth of resources and opportunities that an organization like NinePoint Medical can provide. Whether you are interested in a six-month co-op position, internship, or senior-level role, we value and appreciate your interest in our company.

How to Apply:

All applications are processed online.
To apply for an open position, send an email to hr@ninepointmedical.com with your resume attached.


Equal Opportunity Employer M/F/D/V

Use of search firms: We do not accept unsolicited resumes from search firms or recruiting agencies. If we need the assistance of a search firm, we will contact the firm and require a signed agency agreement. Prospective employees should submit resumes directly online.


900064-Rev4

Main office

Customer Service

1.855.900.7195
617.250.7195
888.979.9197 FAX
customerservice@ninepointmedical.com

Reimbursement questions

Location

One Kendall Square, Suite B7501
Cambridge, MA 02139

NinePoint Medical is located in the heart of Cambridge, Massachusetts,
just steps from the Charles River.

See more. Talk more.

We’d like to hear from you. Please feel free to contact us directly by emailing info@ninepointmedical.com or calling 617.250.7190.


Please wait while we load our new site...